On Pulsatilla

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Pulsatilla saponin D: the antitumor principle from Pulsatilla koreana.

By bioassay-guided separation, an already known saponin, Pulsatilla saponin D was isolated from the root of Pulsatilla koreana Nakai as a antitumor component when evaluated by in vivo antitumor activity as well as in vitro cytotoxic activity test. It showed potent inhibition rate of tumor growth (IR, 82%) at the dose of 6.4 mg/kg on the BDF1 mice bearing LLC cells.

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A new triterpenoid saponin from Pulsatilla cernua.

A new triterpenoid saponin was isolated from Pulsatilla cernua, along with eight known triterpenoids and triterpenoid glycosides. The new compound was identified as 3-O-beta-D-glucopyranosyl-(1-->4)-alpha-L-arabinopyranosyl-bayogenin-28-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester (1) on the basis of 1D, 2D-NMR techniques, including COSY, HMBC, and H...

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Pharmacognostic Standardization of Pulsatilla nigricans Stoerck

Pulsatilla nigricans Linn. (Ranunculaceae) has been traditionally used in the treatment of nervousness, restlessness, ovaritis, ovaralgia, pain associated with debility and due to acute inflammation, uterine affections, acute meningitis, and as taeniafuge, but no work has ever been carried out for standardizing this potential plant. The present investigation establishes histological characters,...

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Staminodial Nectary Structure in Two Pulsatilla (l.) Species

In plants belonging to the Ranunculaceae the floral nectaries may differ in origin, location in the flower, shape and structure. In many cases they are defined as modified tepals or modified stamens. The nectary organs in this family are frequently termed "honey leaves," and staminodial origin is attributed to them. Gynopleural and receptacular nectaries are rarely found in Ranunculaceae. To da...

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Effect of Modified Pulsatilla Powder on Enterotoxigenic Escherichia coli O101-Induced Diarrhea in Mice

MPP can be effective in the treatment of E. coli O101-induced diarrhea in mice. MPP can improve the weight loss caused by diarrhea, increase spleen and thymus indices, and reduce the diarrhea index. MPP can reduce the number of WBC, regulate the level of cytokines, and regulate the intestinal microbial flora. These data suggest that MPP is a promising candidate for treatment of E. coli-induced ...

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ژورنال

عنوان ژورنال: The Boston Medical and Surgical Journal

سال: 1867

ISSN: 0096-6762,1533-4406

DOI: 10.1056/nejm186708290770403